Tag: Study

Long term use of oral bisphosphonates may double risk of esophageal cancer, study finds

People who take oral bisphosphonates for bone disease over five years may be doubling their risk of developing esophageal cancer (cancer of the gullet), according to a new study. (Source: ScienceDaily Headlines)

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Phase II study of biweekly docetaxel and S-1 combination chemotherapy as first-line treatment for advanced gastric cancer

Conclusions  S-1 plus docetaxel combination therapy in an outpatient setting provided promising activity with acceptable adverse toxicities.

Content Type Journal ArticleDOI 10.1007/s00280-010-1433-7Authors
Chikara Kunisaki, Department of Surgery, Gastroenterological Center, Yokohama City University, 4-57 Urafune-cho, Minami-ku, Yokohama, 232-0024 JapanMasazumi Takahashi, Department of Surgery, Yokohama Municipal Hospital, 56 Okazawa-cho, Hodogaya-ku, Yokohama, 240-0062 JapanHirochika Makino, Department of Surgery, Gastroenterological Center, Yokohama City University, 4-57 Urafune-cho, Minami-ku, Yokohama, 232-0024 JapanTakashi Oshima, Department of Surgery, Gastroenterological Center, Yokohama City University, 4-57 Urafune-cho, Minami-ku, Yokohama, 232-0024 JapanShoichi … Source: MedWorm: Oral Cancer

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Exogenous sex hormone use and risk of meningioma: a population-based case–control study in Finland

Conclusions  Overall, we found little indication that reproductive factors or use of exogenous sex hormones affect meningioma risk.

Content Type Journal ArticleDOI 10.1007/s10552-010-9634-2Authors
K. Korhonen, Unit of Neurosurgery, Turku University Hospital, PL 52, 20521 Turku, FinlandJ. Raitanen, School of Public Health, University of Tampere, Tampere, FinlandJ. Isola, Laboratory of Cancer Biology, Institute of Medical Technology, University of Tampere and Tampere University Hospital, Tampere, FinlandH. Haapasalo, Department of Pathology, Tampere University Hospital, Tampere, FinlandT. Salminen, School of Public Health, University of Tampere, Tampere, FinlandA. Auvinen, School of Public Health, University of Tampere, Tampere, Finland

Journal Cancer Causes and Con… Source: MedWorm: Oral Cancer

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Pyridoxine Is Not Effective to Prevent Hand-Foot Syndrome Associated With Capecitabine Therapy: Results of a Randomized, Double-Blind, Placebo-Controlled Study [Treatment-Related Complications]

Conclusion
Pyridoxine is not effective in prevention of capecitabine-associated HFS. (Source: Journal of Clinical Oncology)

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A phase II study of S-1 and oxaliplatin (SOx) combination chemotherapy as a first-line therapy for patients with advanced gastric cancer

Conclusion The SOx regimen evidenced a relatively high response rate and was well tolerated as a first-line therapy for advanced gastric
cancer.

Content Type Journal ArticleDOI 10.1007/s10637-010-9507-2Authors
Sung Yong Oh, Department of Internal Medicine, Dong-A University College of Medicine, Busan, KoreaHyuk-Chan Kwon, Department of Internal Medicine, Dong-A University College of Medicine, Busan, KoreaSang-Ho Jeong, Departments of Surgery, Gyeongsang National University Hospital, Jinju, South KoreaYoung-Tae Joo, Departments of Surgery, Gyeongsang National University Hospital, Jinju, South KoreaYoung-Joon Lee, Departments of Surgery, Gyeongsang National University Hospital, Jinju, South KoreaSu hee Cho, Departments of Internal Medicine, Gyeongsang National University Hospital, Ji… Source: MedWorm: Oral Cancer

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Bisphosphonates Not Linked to Esophageal Cancer, Says Study

A large cohort study examines the possible link between the use of oral bisphosphonates and esophageal and gastric cancers. Medscape Medical News (Source: Medscape Today Headlines)

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Oral contraceptive use associated with increased risk of breast cancer in African-American women, study finds

Researchers have reported that African-American women who use oral contraceptives have a greater likelihood of developing breast cancer than nonusers. The study results were based on data from the Black Women’s Health Study, a large follow-up study of 59,000 African-American women from across the US conducted by investigators at the Slone Epidemiology Center since 1995. (Source: ScienceDaily Headlines)

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Taiwan study finds oral cancer rates up 280 per cent, blames betel

(Source: Monsters and Critics Health News)

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Report of a Multicenter Phase II Trial Testing a Combination of Biweekly Bevacizumab and Daily Erlotinib in Patients With Unresectable Biliary Cancer: A Phase II Consortium Study [Gastrointestinal Cancer]

Conclusion
Combination chemotherapy with bevacizumab and erlotinib showed clinical activity with infrequent grade 3 and 4 adverse effects in patients with advanced biliary cancers. On the basis of preliminary molecular analysis, presence of a k-ras mutation may alter erlotinib efficacy. The combination of bevacizumab and erlotinib may be a therapeutic alternative in patients with advanced biliary cancer. (Source: Journal of Clinical Oncology)

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Researchers study relationship of oral cancers and periodontal disease

(International & American Association for Dental Research) Today during the 88th General Session & Exhibition of the International Association for Dental Research, in Barcelona, Spain, presenting author J. Meyle, Justus Liebig University, Giessen, Germany, will present an abstract titled “P.gingivalis Infection and Immune Evasion of Oral Carcinomas.” (Source: EurekAlert! – Medicine and Health) Source: MedWorm: Oral Cancer

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