Conclusion: Based on the study findings, the combined evaluation of pathologic node status and SUVmax at the primary tumor and regional lymph nodes may improve prognostic stratification in OSCC patients. (Source: International Journal of Radiation Oncology * Biology * Physics)
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Source: MedWorm: Oral Cancer
Tags: Advanced, carcinoma, Cavity, cell, influence, lymph, Maximal, Nodal, Nodes, Oral, Pathological, patients, Plans, primary, Regional, squamous, Standardized, Status, Treatment, tumor, Uptake, value
Abstract: Some classical textbooks of anatomy provided a detailed description of the lingual nodes, which are small inconstant lymph nodes in the floor-of-mouth and the upper neck. The clinical importance of these lymph nodes in cancer therapy, however, has been underestimated so far. We previously reported an extremely poor prognosis of oral tongue cancer patients who had lesions at the root of the lingual artery and assumed that metastases in occult lingual nodes might be responsible for such lesions. This case report clearly demonstrates the distinctive draining course of the lateral lingual nodes, which may potentially be left untreated by a neck dissection. A 63-year-old Japanese male with T2 squamous cell carcinoma of the oral tongue showed multiple metastatic involvements of the lat… Source: MedWorm: Oral Cancer
Tags: Cancer, conventional, dissection, lingual, Metastases, neck, Nodes, pitfall, tongue
Conclusion
For T1 or T2 N0 oral squamous cell carcinoma, SLNB with step sectioning and immunohistochemistry, performed by surgeons of mixed experience levels, correctly predicted a pathologically negative neck in 96% of patients (NPV, 96%). (Source: Journal of Clinical Oncology)
Source: MedWorm: Oral Cancer
Tags: Accurately, Biopsy, Cancer, Carcinomas, cell, head, lymph, MultiInstitutional, neck, Node, Nodes, Oral, Prospective, Regional, Results, Sentinel, squamous, Stages, T1T2, Trial
Conclusion: Although the submandibular content is resected as part of radical and modified radical neck dissections, level I–sparing selective neck dissections could be a safe and effective surgical neck management strategy in appropriately selected patients with OP, Lx, and HP carcinoma. (Source: Otolaryngology – Head and Neck Surgery) Source: MedWorm: Oral Cancer
In early oral squamous cell carcinoma, a sentinel node biopsy correctly predicted an absence of lymphatic metastasis in all but 4% of patients, researchers said. (Source: MedPage Today Hematology/Oncology)
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Source: MedWorm: Oral Cancer
Tags: Cancer, CME/CE, Nodes, Oral, Predict, Sentinel, Spread