Journal of Natural Products, Volume 0, Issue 0, Articles ASAP (As Soon As Publishable). (Source: Journal of Natural Products) Source: MedWorm: Oral Cancer
Tag: effect
Effect of [6]-Shogaol on Cytosolic Ca2+ Levels and Proliferation in Human Oral Cancer Cells (OC2)
Tags: 6Shogaol, Ca2+, Cancer, cells, Cytosolic, effect, human, Levels, Oral, Proliferation
Effect of Body Mass Index on Recurrences in Tamoxifen and Anastrozole Treated Women: An Exploratory Analysis From the ATAC Trial [Breast Cancer]
Conclusion
These results confirm the poorer prognosis of obese women with early-stage breast cancer. Recurrence rates were lower for anastrozole than tamoxifen for all BMI quintiles. Our results suggest that the relative efficacy of anastrozole compared to tamoxifen is greater in thin postmenopausal women and higher doses or more complete inhibitors might be more effective in overweight women, but this requires independent confirmation. (Source: Journal of Clinical Oncology)
Source: MedWorm: Oral Cancer
Tags: analysis, Anastrozole, ATAC, body, Breast, Cancer, effect, exploratory, index, mass, Recurrences, Tamoxifen, treated, Trial, Women
Effect of the menstrual cycle and hormonal contraceptives on human papillomavirus detection in young, unscreened women.
CONCLUSION: High-risk HPV detection was significantly influenced by sample timing in the menstrual cycle when analyzed separately for OCP users and women with a natural menstrual cycle. This may have implications in the future, when high-risk HPV detection may become a primary screening tool in cervical cancer prevention. LEVEL OF EVIDENCE: II.
PMID: 20567170 [PubMed - in process] (Source: Obstetrics and Gynecology)
Source: MedWorm: Oral Cancer
Tags: contraceptives, cycle, Detection, effect, hormonal, human, menstrual, Papillomavirus, unscreened, Women, Young
Potentiating effect of beta-glucans on photodynamic therapy of implanted cancer cells in mice.
Authors: Akramiene D, Aleksandraviciene C, Grazeliene G, Zalinkevicius R, Suziedelis K, Didziapetriene J, Simonsen U, Stankevicius E, Kevelaitis E
Photodynamic therapy (PDT) combines a drug or photosensitizer with a specific type of light to kill cancer cells. The cellular damage induced by PDT leads to activation of the DNA damage repair, which is an important factor for modulating tumor sensitivity to this treatment. beta-Glucans are natural polysaccharides that bind complement receptor 3 on the effector cells, thereby activating them to kill tumor cells during PDT. The hypothesis of the present study was that adjuvant therapy with beta-glucans would increase the efficacy of PDT. C57BL/6 female mice were subcutaneously implanted with Lewis lung carcinoma cells. Ten days after implant…
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Source: MedWorm: Oral Cancer
Tags: betaglucans, Cancer, cells, effect, implanted, mice, photodynamic, Potentiating, therapy
Narrowband Imaging for Early Detection of Malignant Tumors and Radiation Effect After Treatment of Head and Neck Cancer [Original Article]
Conclusion We found that NBI-assisted endoscopy is highly useful for the detection of precancerous lesions in the oropharyngeal and hypopharyngeal mucosa and is not affected by a history of radiotherapy in patients with HNSCC. (Source: Archives of Otolaryngology) Source: MedWorm: Oral Cancer
Tags: after, Article, Cancer, Detection, early, effect, head, imaging, Malignant, Narrowband, neck, Original, radiation, Treatment, Tumors
Celecoxib enhances the inhibitory effect of cisplatin on Tca8113 cells in human tongue squamous cell carcinoma in vivo and in vitro
Conclusions: Those findings indicate that a low dose of celecoxib could augment CDDP-induced growth inhibition of Tca8113 cells and its xenograft in Balb/c nude mice. (Source: Journal of Oral Pathology and Medicine) Source: MedWorm: Oral Cancer
Tags: carcinoma, Celecoxib, cell, cells, cisplatin, effect, enhances, human, inhibitory, squamous, Tca8113, tongue, vitro, vivo
Effect of troglitazone on tumor growth and pulmonary metastasis development of the mouse osteosarcoma cell line LM8
Conclusions:
Inhibition of Akt signaling by TGZ may decrease the secretion of MMP-2, resulting in the decrease of invasiveness and motility in LM8 cells. Treatment of tumor-bearing mice with TGZ decreases the expression and activity of MMP-2 within the tumor, and inhibits primary tumor growth and pulmonary metastasis development. TGZ may offer a new approach in chemotherapy for osteosarcoma. (Source: BMC Cancer)
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Source: MedWorm: Oral Cancer
Tags: cell, development, effect, growth, line, metastasis, mouse, osteosarcoma, pulmonary, troglitazone, tumor
Hepatic protection effect of the alcoholic extract from Camellia sinensis (L.) Kuntze (green tea) in Wistar rats treated with diethylnitrosamine
O chá-verde (Camellia sinensis (L.) Kuntze) é utilizado por suas propriedades: antioxidante, quimioprotetora e antiinflamatória em varias situações patológicas, principalmente frente a compostos químicos cancerígenos. Para tanto se avaliou o efeito hepatoprotetor do extrato de chá verde (ECV) sobre a lipoperoxidação e necrose provocada pelo agente cancerígeno Dietilnitrosamina (DEN) no fígado de ratos machos Wistar. Os ratos foram expostos a dose única de 200 mg/kg de DEN via intra peritoneal e tratados por via oral de 120 mg/kg de ECV em diferentes momentos experimentais. Após 24 h em relação a exposição ao DEN, os animais foram sacrificados sendo avaliado: os níveis de AST/ALT no plasma, a lipoperoxidação por quantificação de TBARS e FOX no fígado e a ocorrência…
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Source: MedWorm: Oral Cancer
Tags: alcoholic, Camellia, diethylnitrosamine, effect, extract, green, Hepatic, Kuntze, protection, rats, sinensis, treated, Wistar