Conclusion: We concluded that PUVA group patients achieved a faster clearance, but the adverse effects were significantly lower in the NBUVB group. (Source: Indian Journal of Dermatology, Venereology and Leprology) Source: MedWorm: Oral Cancer
Treatment Category
Comparative evaluation of NBUVB phototherapy and PUVA photochemotherapy in chronic plaque psoriasis
Tags: Chronic, Comparative, evaluation, NBUVB, photochemotherapy, phototherapy, plaque, psoriasis, PUVA
Quality of life and voice after radiotherapy: speech therapy repercussions
CONCLUSION: many acute and chronic sequelae, such as hoarseness, odinophagy and aphony, involving difficulties in oral communication and/or swallowing in patients after neck and head radiotherapy treatment, interfering with communication, swallowing, and life quality of patients in a direct manner. The professionals involved with the treatment of this cancer, with the speech-language pathologist among them, through the knowledge on the treatment and its therapeutic weaknesses that jeopardize the vocal quality and life quality of those patients, seek to contribute in the recovery process in order to minimize damages caused by the disease and improving the individual’s health condition. (Source: Revista CEFAC)
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Source: MedWorm: Oral Cancer
Tags: after, Life, quality, Radiotherapy, repercussions, speech, therapy, Voice
Desmoglein 3 and keratin 10 expressions are reduced by chronic exposure to cigarette smoke in human keratinised oral mucosa explants
In this study we performed a preliminary light and transmission electron microscopy morphological evaluation focussing in particular on keratinocyte intercellular adhesion and terminal differentiation in chronic smokers.Design: Human biopsies were obtained from healthy young chronic smoker women (n=5) compared with a parallel group of non-smoker healthy volunteers (n=5), as the smoking habit among women is ever more spreading. Samples were processed for light and transmission electron microscopy. On paraffin sections Masson’s and Dane and Herman’s histochemical staining were performed. Biomarker expressions of intercellular adhesion (desmoglein 3, Dsg3), terminal differentiation (keratin 10, K10 and keratin 14, K14), and basal membrane preservation (laminin) were investigated by immunofluo… Source: MedWorm: Oral Cancer
Tags: Chronic, Cigarette, Desmoglein, explants, exposure, expressions., human, keratin, keratinised, Mucosa, Oral, reduced, Smoke
Survival and quality of life of patients with oral and oropharyngeal cancer at 1-year follow-up of tumor resection
This study aimed to assess the survival and life quality evolution of patients subjected to surgical excision of oral and oropharyngeal squamous cell carcinoma. MATERIAL AND METHODS: Forty-seven patients treated at a Brazilian healthcare unit specialized in head and neck surgery between 2006 and 2007 were enrolled in the study. The gathering of data comprised reviewing hospital files and applying the University of Washington Quality of Life (UW-QOL) questionnaire previously and 1 year after the surgery. Comparative analysis used Poisson regression to assess factors associated with survival and a paired t-test to compare preoperative and 1-year postoperative QOL ratings. RESULTS: 1 year after surgery, 7 patients were not found (dropout of the cohort); 15 had died and 25 fulfilled the UW-QOL…
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Source: MedWorm: Oral Cancer
Tags: 1year, Cancer, followup, Life, Oral, oropharyngeal, patients, quality, resection, survival, tumor
Effects of vandetanib on adenoma formation in a dextran sodium sulphate enhanced ApcMIN/+ mouse model.
Authors: Alferez DG, Ryan AJ, Goodlad RA, Wright NA, Wilkinson RW
The ApcMIN/+ mouse is a well-characterised model of intestinal tumourigenesis in which animals develop macroscopically detectable adenomas. However, most of the adenomas are formed in the small intestine and resolution of events in the colon, the most relevant site for human disease, is limited. Inducing colitis with dextran sodium sulphate (DSS) can selectively enhance the development of lesions in the colon. We demonstrated that a DSS pre-treatment is well tolerated and effective at inducing colon adenomas in an ApcMIN/+ mouse model. We then investigated the effect of inhibiting vascular endothelial growth factor (VEGFR)- and epidermal growth factor receptor (EGFR)-dependent signalling pathways on the development of ad…
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Source: MedWorm: Oral Cancer
Tags: adenoma, ApcMIN/+, dextran, effects, enhanced, formation, model, mouse, sodium, sulphate, Vandetanib
Efforts By Dentist Couple Toward Dental Health of Family
Summer time, means kids have lots of free time for junk food, snacks and the toothaches that they can cause. A whole family can get professional dental health care at a new address. A husband and wife who are both dentists own and run this professional practice. As dentists, the husband was in the US Army Dental Corps for six years while the wife became a dental hygienist. Both were stationed in Europe, and Cindy’s work encompassed her helping to initiate a public dental health program in the northern region of Europe, where they were based. You will gain a deeper understanding about <a rel=”nofollow” onclick=”javascript:_gaq.push(['_trackPageview', '/outgoing/article_exit_link']);” href=’http://www.cosmeticdentistglebe.com.au’>sydney dentist</a> by checking out that resource. They provide general dentistry services, inclusive of cleaning, fillings, and root canals. The husband gives aesthetic fillings, cosmetic bonding techniques, full mouth reconstructive surgery as well. He believes in dental care that prevents the spread of dental diseases. Prevention and educating people on better dental care is the aim of modern dentistry. This creed is something we firmly believe to be true and spend a considerable amount of time to help our patients learn the basics of dental hygiene. He recommends brushing after every meal, even snacks if possible. Damaged gums could be the result of brushing too hard. Cleaning is more effective with a soft tooth brush. When you have learned to floss, practice making it a habit. Many kinds of floss exist, including those with peppermint flavors. If you’re an adult, use a fluoride rinse and find out if your children need sealants for cavity prevention. Quit smoking, he advises all smokers. If you are a non smoker, stay that way. It’s not a mystery for most that lung cancer is a result of smoking. There are not so many who know, though, that cancer of the mouth and throat develops also because of smoking. When you would like to get more information on <a rel=”nofollow” onclick=”javascript:_gaq.push(['_trackPageview', '/outgoing/article_exit_link']);” href=’http://www.cosmeticdentistglebe.com.au’>dental surgery sydney</a> check out this site. When you find a sore on the lips, gums, or inside the mouth that just doesn’t seem to heal, then it could be a sign of oral cancer. To know if you may be suffering from oral cancer, look for indicators such as unexplainable mouth bleeding or swelling of the tongue and lips. Don’t delay as soon as you notice anything out of the ordinary in your mouth. Stop by your dentist’s office at the soonest possible time. Finding out early on if a person has oral cancer would make successful treatment possible. Periodontal gum disease is another major problem that affects the tissues and bones surrounding and supporting teeth. Periodontal disease is a major reason for why adults experience tooth loss. About 75% of adults would, in the course of the lives, suffer a certain form of gum disease. Detectives can spot periodontal gum diseases by employing methods in periodontal examination, such as probing around the tooth and taking x rays. If you brush your teeth, check for bleeding gums, which are one of the warning signs. Gums that are separated from the teeth or are red, swollen or tender. Another indicator would be infected areas between your teeth and gums. Gum disease warning signs also include loose teeth or changes in their position.
Tags: Couple, Dental, Dentist, Efforts, Family, Health, Toward
Bisphosphonates may double cancer risk
Long-term oral bisphosphonates may double risk of oesophageal cancerRelated items from OnMedicaBisphosphonate use does not raise cancer riskMortality higher if using paroxetine and tamoxifenNew osteoporosis risk scores highly effectiveFalls prevention services are not evidence-basedBenefits of statins ’still outweigh risks’ (Source: OnMedica Latest News) Source: MedWorm: Oral Cancer
Tags: Bisphosphonates, Cancer, double, risk
How To Prevent Wrinkles With Time
Good habits and good genes can only take you so far when you’re competing against the biological clock. Like it or not, there will come a day when you’ll look in the mirror and realize that some of those “smile lines” are sticking around.
You probably know that day can be delayed if you eat right, exercise and guard against the sun. But if you, like the rest of us, don’t always succeed with the healthy-lifestyle approach, turn to this list of fallback options from Charlene Haines of Euphoria Day Spa.
A truly blissful option, this facial cleanses, hydrates and exfoliates the skin while it pumps in plenty of fresh air, improving circulation, stimulating cell rejuvenation and killing any blemish-causing bacteria hiding in pores. Ever wonder how celebs like Jennifer Aniston look so luminous even without makeup? Now you know.
This common procedure involves using small needles to inject traces of a substance that “paralyzes” the muscles underneath, where lines are forming usually around the mouth and eyes and on the forehead. It temporarily freezes the muscles that form these expression lines, cutting down on the repetitive movements that help create wrinkles.
It’s fast, easy and relatively painless, but make sure to pick a doctor with experience, and undergo an allergy test first. You’ll have to get Botox shots every few months, but the results are dramatic and, over the long haul, can delay the formation of wrinkles.
Gone are the days of lumpy, bumpy injections to plump up lips and sagging cheeks. Now it’s all about Restylane or Radiesse, two natural fillers made of hyaluronic acid (a natural substance already present in the human body) that are injected right into creases and wrinkles to make them disappear.
The effects last for about six months and are less prone to infection and clumping than previous treatments. Britney Spears uses Restylane to give her bow-tie lips a slightly fuller look.
A highly effective procedure that’s one step below a laser treatment, this is actually nothing like a facial. Doctors turn an intense, pulsating light on your skin (officially known as nonablative rejuvenation) that fades pigmentation, reduces large pores, clears up acne and really does a number on fine lines and wrinkles. It’s quick and fairly painless (you might feel a slight zap) and can take 10 years off your skin in a matter of minutes.
Non-Surgical Face-Lift One of the newest anti-wrinkle options to hit the market, this medical device uses radio-frequency technology to eradicate lines and wrinkles that formerly could be reduced only with a surgical lift.
It works by chilling the skin and then applying tightening energy from radio frequency. It’s not entirely without discomfort, but the results are worth it. Dermatologists prep patients with a topical anesthetic and a strong painkiller before getting busy.
Unless things are really headed south, Charlene advises, don’t go under the plastic surgeon’s knife. Radical procedures like face-lifts will yield disappointing results if they’re done too early, she says. Better to prevent problems today so you won’t have to fix them tomorrow.
A Plastic Surgeon is a surgical specialist who has completed a minimum of 5 years of study and training in surgery after receiving a medical degree. He or she has demonstrated successful completion of training and passed a rigorous examination process overseen by the Royal College of Physicians and Surgeons of Canada and is thus specifically qualified to practice reconstructive and aesthetic (cosmetic) plastic surgery.
Most people are familiar with cosmetic surgery. Plastic Surgeons are the experts in cosmetic surgery. However, many people do not realize that Plastic Surgeons also look after most of the hand and facial injuries in Canada.
They manage most large wounds including burns. Canadian Plastic Surgeons treat a large number of patients with skin cancer, and they help the rehabilitation of breast cancer patients with breast reconstruction. They repair congenital deformities like cleft lips and abnormal hands. They participate in leg, hand, face, and skull reconstruction after severe accidents.
In fact, if any part of the body is abnormal or needs reconstruction to restore function or appearance after birth, cancer or accidents, Plastic Surgeons are there to help.
Osteoporosis drug linked to cancer
OXFORD, England, Sept. 3 (UPI) — Long-term use of oral bisphosphonates — used to prevent bone loss — may double the risk of developing esophageal cancer, researchers in Britain say.
Osteoporosis – Esophageal cancer – Health – Cancer – England (Source: Health News – UPI.com) Source: MedWorm: Oral Cancer
Tags: Cancer, Drug, linked, Osteoporosis
Ingredients in Your Lipstick ? Is Your Health At Risk?
Lipstick ingredients in many cases are a noxious blend of petroleum based chemicals, many of which have not been thoroughly tested for safety. A number of these ingredients may cause allergic reactions or interfere with your body’s hormones. Some can even harm important body systems like your nervous system and immune system.
Who would have ever thought that the pretty colors that help you look beautiful can actually cause harm? The truth of the matter is that many of the ingredients that color your lipstick are derived from coal tar, which causes cancer. Now, these color ingredients may not themselves be known to cause cancer, but a great deal of them have not been adequately tested to determine if they’re safe.
Most of the color ingredients in your lipstick that give you an amazing number of shades to choose from are D&C and FD&C colors, i.e. artificial colors. However, the majority of the time, the D&C and FD&C are left off the label so you’ll see the color listed something like “Orange 5″ or “Blue 1 Lake.”
Why should this matter to you?
The FDA has approved D&C Colors for drugs and cosmetics but not for food. So they can’t be used in things you eat. Now, in spite of the fact that lipstick is a cosmetic and not a food, everyone who wears it eats it. Every time you lick your lips, you’re eating a little bit of lipstick. In fact, “in the June 2002 issue of Glamour magazine it was reported that women inadvertently ingest about 4 pounds of lipstick in their lifetime.”
The other artificial colors used in lipstick, FD&C Colors, have been approved by the FDA for food, drugs and cosmetics.
D&C and FD&C Colors are regulated by the FDA, but only in terms of the amount of the toxic metals, lead and arsenic, they contain. D&C Colors may not contain more than 20 ppm [parts per million] of lead and arsenic. FD&C Colors are limited to 10 ppm.
Lead and arsenic are poisonous. So, every time you lick your lips you may be getting a small dose of these noxious chemicals.
Tests done on a number of different lipstick brands in 2007 for the presence of lead found that in over half of the brands tested the level of lead was more than what’s allowed in candy. More recently, the FDA tested 22 brands of lipstick and found lead in every single one and at even higher levels than the 2007 study! Nevertheless, the FDA considers the lead detected in the lipstick tested to be harmless. However, considering that lead accumulates in your body, and even minute amounts of lead in lipstick can lead to harm, do you want to be adding lead to your body every time you lick your lips?
It’s important to note here that the certification of D&C and FD&C Colors does not address any other harmful effects these colors may have on your body. For example, neither the D&C nor FD&C Colors are checked to determine if they cause allergic reactions, are skin irritants, whether they’re toxic to your nervous system or reproductive system or even cause cancer.
In addition, a great deal of what you put on your skin is absorbed directly into your bloodstream. This fact is NOT taken into consideration in the standards for D&C Colors, which allow twice as much of the toxic lead and arsenic as the FD&C Colors.
Avoid these D&C Colors commonly found in lipstick:
• Orange 5
• Orange 5 Lake
• Red 6
• Red 6 Lake
• Red 7 Lake
• Red 21
• Red 21 Lake
• Red 27
• Red 27 Lake
• Red 30 Lake
• Red 33 Lake
Stay away from these FD&C Color ingredients found in lipstick as well:
• Blue 1 Lake
• Yellow 5 Lake
• Yellow 6 Lake
This is just a sampling of the kinds of color ingredients you may find in your lipstick. When you check the ingredients list on your lipstick, you may find other color ingredients that are not listed here, but should be avoided. For example, it’s best to pass up any lipsticks that contain any color ingredients with a number after it, or with a number and “lake.”
Also, there are other harmful ingredients in your lipstick besides colors. These include xenoestrogens or endocrine disruptors, which interfere with your hormones. Some common ones found in lipstick are parabens. Methylparaben and propylparaben are the ones most frequently found in lipstick.
Another kind of ingredient you want to pass up is the penetration enhancer. It causes more of the ingredients in your lipstick to be absorbed into your body. An example of a common penetration enhancer found in lipstick as well as other cosmetic products is propylene glycol.
By now, you’re probably wondering how you’re supposed to protect yourself.
Here’s a simple way to get started using healthier lipstick and cosmetic products:
Check the ingredients list for the chemicals listed above when you shop for lipstick as well as all your other cosmetic products. Then choose only those products that are free of these harmful ingredients. You may need a magnifying to read the tiny print. Do this and you’ll be off to a good start.
Tags: Health, Ingredients, Lipstick, risk